ARRONAX operates the world-wide only C70XP cyclotron, a high-intensity multi-particle cyclotron that supplies proton beams up to 70 MeV and 350 μA as well as deuteron beams up to 35 MeV and ɑ particle beams of 68 MeV. Appropriate targetry and radiochemical separation is developed in-house. As one of few facilities worldwide, ARRONAX holds an FDA certification for Sr-82 as an active pharmaceutical ingredient. ARRONAX is the only European producer of Sr-82 and the leading producer of Cu-64, Pb-203, Ru-97 and At-211 in France. Cu-64 has been already used in a clinical trial (NCT03951337). Pb-203 is available as API under GMP. As Day-1 radionuclides, ARRONAX can provide Pb-203 in ammonium acetate in GMP quality, Cu-64 as Cu-64Cl2 or Cu-64-ATSM, At-211 as a dry residue. Ru-97 and Hg197m/Hg-197 can also be supplied for chemistry studies or preclinical experiments respectively (depending on required activities). |
